I started my new medication this weekend, that included a new wonder drug called Rybelsus. Now this is a semiglutide similar to Ozempic, Mounjaro, Wegovy etc. The only difference is it’s a pill taken orally instead of the once-weekly injection that the other medications are. Now, I tried Ozempic when it was still mostly used for diabetes, and it was working great. As soon as I went from the starter dose to the next step, however, the side effects started hitting me hard. I was so sick I thought I had the stomach flu. Nausea, vomiting, excessive fountain pooping . . . and it lasted for months. We didn’t connect it to the Ozempic at first because I didn’t have any of those side effects on the lower dose. It ended up with me in the hospital after blacking out and slicing my hand open while I was unconscious.

Flash forward to years later, about 2 years ago, when my (new, then) doctor decided to try Mounjaro. I was up front with the doctor about my previous GLP-1 woes and my concerns about trying another, but reluctantly agreed to try with the assurances we’d stop if we started to notice the same side effects trending . I gave it about three months, and started struggling with the same issues, so had to go off it then. I was disappointed, but resigned myself to not being able to take any of the weight loss medications.

This medication you have to take 30 minutes before you put anything else into your mouth in the morning, with at least 4 oz of water. Saturday was my first dose and I started noticing the food noise in my head and the hunger all the time was starting to dissipate. Sunday morning, I didn’t eat until well after noon and even then it was because I knew I needed to. That was a feeling I needed to feel, because the last two weeks have stressed me out post-surgery with all the “food noise” going around. This is going to be wonderful! I’m so excited for this new Rybelsus journey.